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Depleting deubiquitinating enzymes promotes apoptosis in glioma cell line via RNA binding proteins SF2/ASF1

USP5 and USP8 (Deubiquitinating enzyme) are highly overexpressed and more recognized as poor prognosis marker in various cancers. Depleting USP5 or USP8 to assess the synergism with proteasome inhibitor (Bortezomib) were measured. Furthermore, in present finding USP5 cooperates hnRNPA1 & USP8 co...

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Detalles Bibliográficos
Autores principales: Vashistha, Vidhi, Bhardwaj, Sachin, Yadav, Birendra K., Yadav, Ajay K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726668/
https://www.ncbi.nlm.nih.gov/pubmed/33319070
http://dx.doi.org/10.1016/j.bbrep.2020.100846