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Structure-Based Scaffold Repurposing toward the Discovery of Novel Cholinesterase Inhibitors
[Image: see text] Cholinesterases (ChE) are well-known drug targets for the treatment of Alzheimer’s disease (AD). In continuation of work to develop novel cholinesterase inhibitors, we utilized a structure-based scaffold repurposing approach and discovered six novel ChE inhibitors from our recently...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726787/ https://www.ncbi.nlm.nih.gov/pubmed/33324805 http://dx.doi.org/10.1021/acsomega.0c03848 |