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Alternative splicing coupled mRNA decay shapes the temperature‐dependent transcriptome

Mammalian body temperature oscillates with the time of the day and is altered in diverse pathological conditions. We recently identified a body temperature‐sensitive thermometer‐like kinase, which alters SR protein phosphorylation and thereby globally controls alternative splicing (AS). AS can gener...

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Detalles Bibliográficos
Autores principales: Neumann, Alexander, Meinke, Stefan, Goldammer, Gesine, Strauch, Miriam, Schubert, Daniel, Timmermann, Bernd, Heyd, Florian, Preußner, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726792/
https://www.ncbi.nlm.nih.gov/pubmed/33140569
http://dx.doi.org/10.15252/embr.202051369