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Function of the SNARE Ykt6 on autophagosomes requires the Dsl1 complex and the Atg1 kinase complex

The mechanism and regulation of fusion between autophagosomes and lysosomes/vacuoles are still only partially understood in both yeast and mammals. In yeast, this fusion step requires SNARE proteins, the homotypic vacuole fusion and protein sorting (HOPS) tethering complex, the RAB7 GTPase Ypt7, and...

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Detalles Bibliográficos
Autores principales: Gao, Jieqiong, Kurre, Rainer, Rose, Jaqueline, Walter, Stefan, Fröhlich, Florian, Piehler, Jacob, Reggiori, Fulvio, Ungermann, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726795/
https://www.ncbi.nlm.nih.gov/pubmed/33025734
http://dx.doi.org/10.15252/embr.202050733