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An intact membrane is essential for small extracellular vesicle‐induced modulation of α‐synuclein fibrillization

The misfolding and fibrillization of the protein, α‐synuclein (αsyn), is associated with neurodegenerative disorders referred to as the synucleinopathies. Understanding the mechanisms of αsyn misfolding is an important area of interest given that αsyn misfolding contributes to disease pathogenesis....

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Detalles Bibliográficos
Autores principales: Ugalde, Cathryn L., Gordon, Shane E., Shambrook, Mitch, Nasiri Kenari, Amirmohammad, Coleman, Bradley M., Perugini, Matthew A., Lawson, Victoria A., Finkelstein, David I., Hill, Andrew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726797/
https://www.ncbi.nlm.nih.gov/pubmed/33318779
http://dx.doi.org/10.1002/jev2.12034