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MLLT6 maintains PD‐L1 expression and mediates tumor immune resistance

Tumor cells subvert immune surveillance by harnessing signals from immune checkpoints to acquire immune resistance. The protein PD‐L1 is an important component in this process, and inhibition of PD‐L1 elicits durable anti‐tumor responses in a broad spectrum of cancers. However, immune checkpoint inh...

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Detalles Bibliográficos
Autores principales: Sreevalsan, Sandeep, Döring, Marietta, Paszkowski‐Rogacz, Maciej, Brux, Melanie, Blanck, Carolina, Meyer, Marten, Momburg, Frank, Buchholz, Frank, Theis, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726806/
https://www.ncbi.nlm.nih.gov/pubmed/33063451
http://dx.doi.org/10.15252/embr.202050155