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Atg1 kinase regulates autophagosome‐vacuole fusion by controlling SNARE bundling

Autophagy mediates the degradation of cytoplasmic material. Upon autophagy induction, autophagosomes form a sealed membrane around the cargo and fuse with the lytic compartment to release the cargo for degradation. In order to avoid premature fusion of immature autophagosomal membranes with the lyti...

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Detalles Bibliográficos
Autores principales: Barz, Saskia, Kriegenburg, Franziska, Henning, Anna, Bhattacharya, Anuradha, Mancilla, Hector, Sánchez‐Martín, Pablo, Kraft, Claudine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726815/
https://www.ncbi.nlm.nih.gov/pubmed/33274589
http://dx.doi.org/10.15252/embr.202051869