Targeting of the Alox12-12-HETE in Blast Crisis Chronic Myeloid Leukemia Inhibits Leukemia Stem/Progenitor Cell Function

INTRODUCTION: Chronic myeloid leukemia (CML) is a myeloid malignancy characterized by the oncogene BCR-ABL. CML responds well to therapy targeting BCR-ABL in the chronic phase but is resistant to treatment when it progresses to the blast phase (BP). This study attempted to address whether arachidona...

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Detalles Bibliográficos
Autores principales: Gao, Si, Hu, Jialin, Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726836/
https://www.ncbi.nlm.nih.gov/pubmed/33312001
http://dx.doi.org/10.2147/CMAR.S280554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726836/
https://www.ncbi.nlm.nih.gov/pubmed/33312001
http://dx.doi.org/10.2147/CMAR.S280554

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