Long non-coding RNA HOTAIR induces GLI2 expression through Notch signalling in systemic sclerosis dermal fibroblasts

OBJECTIVES: Systemic sclerosis (SSc) is characterised by tissue fibrosis of the major organs of the body including the skin, lungs and heart. We have previously reported that the lncRNA HOTAIR plays a central role in the activation of SSc myofibroblasts, the key cellular elements of fibrosis. HOTAIR...

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Detalles Bibliográficos
Autores principales: Wasson, Christopher W., Ross, Rebecca L., Wells, Rebecca, Corinaldesi, Clarissa, Georgiou, Ioanna Ch., Riobo-Del Galdo, Natalia A., Del Galdo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726858/
https://www.ncbi.nlm.nih.gov/pubmed/33303026
http://dx.doi.org/10.1186/s13075-020-02376-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726858/
https://www.ncbi.nlm.nih.gov/pubmed/33303026
http://dx.doi.org/10.1186/s13075-020-02376-9

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