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Circular RNA circPLK1 promotes breast cancer cell proliferation, migration and invasion by regulating miR-4500/IGF1 axis

BACKGROUND: Circular RNAs (circRNAs) can regulate gene expression in different malignancies. However, the biological functions of circRNA polo-like kinase-1 (circPLK1) in the tumorigenesis of breast cancer (BC) and its potential mechanisms have not been well elucidated yet. METHODS: The expression l...

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Detalles Bibliográficos
Autores principales: Lin, Guanhong, Wang, Shenyu, Zhang, Xinyu, Wang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726896/
https://www.ncbi.nlm.nih.gov/pubmed/33298061
http://dx.doi.org/10.1186/s12935-020-01694-x