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Regulator of G‐Protein Signaling 5 Maintains Brain Endothelial Cell Function in Focal Cerebral Ischemia

BACKGROUND: Regulator of G‐protein signaling 5 (RGS5) is a negative modulator of G‐protein–coupled receptors. The role of RGS5 in brain endothelial cells is not known. We hypothesized that RGS5 in brain microvascular endothelial cells may be an important mediator of blood‐brain barrier function and...

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Detalles Bibliográficos
Autores principales: Sladojevic, Nikola, Yu, Brian, Liao, James K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726987/
https://www.ncbi.nlm.nih.gov/pubmed/32875943
http://dx.doi.org/10.1161/JAHA.120.017533