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MerTK Expression and ERK Activation Are Essential for the Functional Maturation of Osteopontin‐Producing Reparative Macrophages After Myocardial Infarction

BACKGROUND: We previously reported that osteopontin plays an essential role in accelerating both reparative fibrosis and clearance of dead cells (efferocytosis) during tissue repair after myocardial infarction (MI) and galectin‐3(hi)CD206(+) macrophages is the main source of osteopontin in post‐MI h...

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Detalles Bibliográficos
Autores principales: Shirakawa, Kohsuke, Endo, Jin, Kataoka, Masaharu, Katsumata, Yoshinori, Anzai, Atsushi, Moriyama, Hidenori, Kitakata, Hiroki, Hiraide, Takahiro, Ko, Seien, Goto, Shinichi, Ichihara, Genki, Fukuda, Keiichi, Minamino, Tohru, Sano, Motoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7726992/
https://www.ncbi.nlm.nih.gov/pubmed/32865099
http://dx.doi.org/10.1161/JAHA.120.017071