Transcriptomic profiles in pulmonary arterial hypertension associate with disease severity and identify novel candidate genes

Using RNAseq, we identified a 61 gene-based circulating transcriptomic profile most correlated with four indices of pulmonary arterial hypertension severity. In an independent dataset, 13/61 (21%) genes were differentially expressed in lung tissues of pulmonary arterial hypertension cases versus con...

Descripción completa

Detalles Bibliográficos
Autores principales: Romanoski, Casey E., Qi, Xinshuai, Sangam, Shreya, Vanderpool, Rebecca R., Stearman, Robert S., Conklin, Austin, Gonzalez-Garay, Manuel, Rischard, Franz, Ayon, Ramon J., Wang, Jian, Simonson, Tatum, Babicheva, Aleksandra, Shi, Yinan, Tang, Haiyang, Makino, Ayako, Kanthi, Yogendra, Geraci, Mark W., Garcia, Joe G.N., Yuan, Jason X.-J., Desai, Ankit A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727059/
https://www.ncbi.nlm.nih.gov/pubmed/33343881
http://dx.doi.org/10.1177/2045894020968531

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727059/
https://www.ncbi.nlm.nih.gov/pubmed/33343881
http://dx.doi.org/10.1177/2045894020968531

Ejemplares similares