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Trdmt1 3'-untranslated region functions as a competing endogenous RNA in leukemia HL-60 cell differentiation

Severe blockage in myeloid differentiation is the hallmark of acute myeloid leukemia (AML). Trdmt1 plays an important role in hematopoiesis. However, little is known about the function of Trdmt1 in AML cell differentiation. In the present study, Trdmt1 was up-regulated and miR-181a was down-regulate...

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Detalles Bibliográficos
Autores principales: Xu, Sha, Xiong, Jun, Wu, Minjuan, Yang, Yu, Jiang, Junfeng, Ni, Haitao, Zhao, Yunpeng, Wang, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727116/
https://www.ncbi.nlm.nih.gov/pubmed/33331537
http://dx.doi.org/10.1590/1414-431X20209869