Semaphorin 3A mediated brain tumor stem cell proliferation and invasion in EGFRviii mutant gliomas

BACKGROUND: Glioblastoma multiforme (GBM) is the most common primary brain tumor in adults, with a median survival of approximately 15 months. Semaphorin 3A (Sema3A), known for its axon guidance and antiangiogenic properties, has been implicated in GBM growth. We hypothesized that Sema3A directly in...

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Detalles Bibliográficos
Autores principales: Higgins, Dominique M. O., Caliva, Maisel, Schroeder, Mark, Carlson, Brett, Upadhyayula, Pavan S., Milligan, Brian D., Cheshier, Samuel H., Weissman, Irving L., Sarkaria, Jann N., Meyer, Fredric B., Henley, John R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727139/
https://www.ncbi.nlm.nih.gov/pubmed/33302912
http://dx.doi.org/10.1186/s12885-020-07694-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727139/
https://www.ncbi.nlm.nih.gov/pubmed/33302912
http://dx.doi.org/10.1186/s12885-020-07694-4

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