Integrating expert opinions with clinical trial data to analyse low-powered subgroup analyses: a Bayesian analysis of the VeRDiCT trial

BACKGROUND: Typically, subgroup analyses in clinical trials are conducted by comparing the intervention effect in each subgroup by means of an interaction test. However, trials are rarely, if ever, adequately powered for interaction tests, so clinically important interactions may go undetected. We d...

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Detalles Bibliográficos
Autores principales: Thirard, Russell, Ascione, Raimondo, Blazeby, Jane M., Rogers, Chris A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Technical Advance
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727208/
https://www.ncbi.nlm.nih.gov/pubmed/33302878
http://dx.doi.org/10.1186/s12874-020-01178-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727208/
https://www.ncbi.nlm.nih.gov/pubmed/33302878
http://dx.doi.org/10.1186/s12874-020-01178-6

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