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Can harmonisation of outcomes bridge the translation gap for pre-clinical research? A systematic review of outcomes measured in mouse models of type 2 diabetes

BACKGROUND: In pre-clinical research, systematic reviews have the potential to mitigate translational challenges by facilitating understanding of how pre-clinical studies can inform future clinical research. Yet their conduct is encumbered by heterogeneity in the outcomes measured and reported, and...

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Detalles Bibliográficos
Autores principales: Harman, Nicola L., Sanz-Moreno, Adrián, Papoutsopoulou, Stamatia, Lloyd, Katie A., Ameen-Ali, Kamar E., Macleod, Malcolm, Williamson, Paula R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727210/
https://www.ncbi.nlm.nih.gov/pubmed/33298112
http://dx.doi.org/10.1186/s12967-020-02649-6