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High-expression of ROCK1 modulates the apoptosis of lens epithelial cells in age-related cataracts by targeting p53 gene

BACKGROUND: Age-related cataract (ARC) is a serious visual impairment disease, and its pathogenesis is unclear. This article aims to investigate the role of ROCK1 in the apoptosis of lens epithelial cells (LECs) in age-related cataracts. METHODS: We collect anterior capsule samples from normal peopl...

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Detalles Bibliográficos
Autores principales: Hu, Shanshan, Su, Dongmei, Sun, Lei, Wang, Zhongying, Guan, Lina, Liu, Shanhe, Zhao, Baowen, Liu, Yong, Shi, Cuige, Yu, Jianbo, Ma, Xu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727231/
https://www.ncbi.nlm.nih.gov/pubmed/33297931
http://dx.doi.org/10.1186/s10020-020-00251-6