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AFF3-DNA methylation interplay in maintaining the mono-allelic expression pattern of XIST in terminally differentiated cells

X chromosome inactivation and genomic imprinting are two classic epigenetic regulatory processes that cause mono-allelic gene expression. In female mammals, mono-allelic expression of the long non-coding RNA gene X-inactive specific transcript (XIST) is essential for initiation of X chromosome inact...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Wang, Chao, Liu, Xiaoxu, Yang, Qian, Ji, Hongliang, Yang, Mengjun, Xu, Manman, Zhou, Yunyan, Xie, Wei, Luo, Zhuojuan, Lin, Chengqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727261/
https://www.ncbi.nlm.nih.gov/pubmed/30535390
http://dx.doi.org/10.1093/jmcb/mjy074