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DICER1 regulates antibacterial function of epididymis by modulating transcription of β-defensins

DICER1 is a key enzyme responsible for the maturation of microRNAs. Recent evidences suggested that DICER1 and microRNAs expressed in epididymis were involved in the control of male fertility. However, the exact mechanism remains to be elucidated. Here, we created a mouse line by targeted disruption...

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Detalles Bibliográficos
Autores principales: Tang, Chunhua, Ni, Minjie, Xie, Shengsong, Zhang, Yao, Zhang, Chaobao, Ni, Zimei, Chu, Chen, Wu, Ligang, Zhou, Yuchuan, Zhang, Yonglian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727269/
https://www.ncbi.nlm.nih.gov/pubmed/30215742
http://dx.doi.org/10.1093/jmcb/mjy048