Dynamics of Internalization and Intracellular Interaction of Tau Antibodies and Human Pathological Tau Protein in a Human Neuron-Like Model

We and others have shown in various in vivo, ex vivo and cell culture models that several tau antibodies interact with pathological tau within neurons. To further clarify this interaction in a dynamic human model, we differentiated SH-SY5Y cells with retinoic acid and BDNF to create a neuron-like mo...

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Detalles Bibliográficos
Autores principales: Shamir, Dov B., Deng, Yan, Wu, Qian, Modak, Swananda, Congdon, Erin E., Sigurdsson, Einar M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727311/
https://www.ncbi.nlm.nih.gov/pubmed/33324339
http://dx.doi.org/10.3389/fneur.2020.602292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727311/
https://www.ncbi.nlm.nih.gov/pubmed/33324339
http://dx.doi.org/10.3389/fneur.2020.602292

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