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Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring

Folate is an essential micronutrient required for both cellular proliferation through de novo nucleotide synthesis and epigenetic regulation of gene expression through methylation. This dual requirement places a particular demand on folate availability during pregnancy when both rapid cell generatio...

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Detalles Bibliográficos
Autores principales: Harlan De Crescenzo, Angelo, Panoutsopoulos, Alexios A, Tat, Lyvin, Schaaf, Zachary, Racherla, Shailaja, Henderson, Lyle, Leung, Kit-Yi, Greene, Nicholas D E, Green, Ralph, Zarbalis, Konstantinos S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727343/
https://www.ncbi.nlm.nih.gov/pubmed/32995858
http://dx.doi.org/10.1093/cercor/bhaa248