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Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring
Folate is an essential micronutrient required for both cellular proliferation through de novo nucleotide synthesis and epigenetic regulation of gene expression through methylation. This dual requirement places a particular demand on folate availability during pregnancy when both rapid cell generatio...
Autores principales: | Harlan De Crescenzo, Angelo, Panoutsopoulos, Alexios A, Tat, Lyvin, Schaaf, Zachary, Racherla, Shailaja, Henderson, Lyle, Leung, Kit-Yi, Greene, Nicholas D E, Green, Ralph, Zarbalis, Konstantinos S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727343/ https://www.ncbi.nlm.nih.gov/pubmed/32995858 http://dx.doi.org/10.1093/cercor/bhaa248 |
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