The Genetic Basis of Primary Myelofibrosis and Its Clinical Relevance

Among classical BCR-ABL-negative myeloproliferative neoplasms (MPN), primary myelofibrosis (PMF) is the most aggressive subtype from a clinical standpoint, posing a great challenge to clinicians. Whilst the biological consequences of the three MPN driver gene mutations (JAK2, CALR, and MPL) have bee...

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Detalles Bibliográficos
Autores principales: Rumi, Elisa, Trotti, Chiara, Vanni, Daniele, Casetti, Ilaria Carola, Pietra, Daniela, Sant’Antonio, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727658/
https://www.ncbi.nlm.nih.gov/pubmed/33255170
http://dx.doi.org/10.3390/ijms21238885

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727658/
https://www.ncbi.nlm.nih.gov/pubmed/33255170
http://dx.doi.org/10.3390/ijms21238885

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