Antibody Fragments as Tools for Elucidating Structure-Toxicity Relationships and for Diagnostic/Therapeutic Targeting of Neurotoxic Amyloid Oligomers

The accumulation of amyloid protein aggregates in tissues is the basis for the onset of diseases known as amyloidoses. Intriguingly, many amyloidoses impact the central nervous system (CNS) and usually are devastating diseases. It is increasingly apparent that neurotoxic soluble oligomers formed by...

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Detalles Bibliográficos
Autores principales: Bitencourt, André L. B., Campos, Raquel M., Cline, Erika N., Klein, William L., Sebollela, Adriano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727795/
https://www.ncbi.nlm.nih.gov/pubmed/33255488
http://dx.doi.org/10.3390/ijms21238920

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727795/
https://www.ncbi.nlm.nih.gov/pubmed/33255488
http://dx.doi.org/10.3390/ijms21238920

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