Melatonin Rescues the Dendrite Collapse Induced by the Pro-Oxidant Toxin Okadaic Acid in Organotypic Cultures of Rat Hilar Hippocampus

The pro-oxidant compound okadaic acid (OKA) mimics alterations found in Alzheimer’s disease (AD) as oxidative stress and tau hyperphosphorylation, leading to neurodegeneration and cognitive decline. Although loss of dendrite complexity occurs in AD, the study of this post-synaptic domain in chemical...

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Detalles Bibliográficos
Autores principales: Solís-Chagoyán, Héctor, Domínguez-Alonso, Aline, Valdés-Tovar, Marcela, Argueta, Jesús, Sánchez-Florentino, Zuly A., Calixto, Eduardo, Benítez-King, Gloria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727803/
https://www.ncbi.nlm.nih.gov/pubmed/33255515
http://dx.doi.org/10.3390/molecules25235508

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727803/
https://www.ncbi.nlm.nih.gov/pubmed/33255515
http://dx.doi.org/10.3390/molecules25235508

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