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Melatonin Rescues the Dendrite Collapse Induced by the Pro-Oxidant Toxin Okadaic Acid in Organotypic Cultures of Rat Hilar Hippocampus
The pro-oxidant compound okadaic acid (OKA) mimics alterations found in Alzheimer’s disease (AD) as oxidative stress and tau hyperphosphorylation, leading to neurodegeneration and cognitive decline. Although loss of dendrite complexity occurs in AD, the study of this post-synaptic domain in chemical...
Autores principales: | Solís-Chagoyán, Héctor, Domínguez-Alonso, Aline, Valdés-Tovar, Marcela, Argueta, Jesús, Sánchez-Florentino, Zuly A., Calixto, Eduardo, Benítez-King, Gloria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7727803/ https://www.ncbi.nlm.nih.gov/pubmed/33255515 http://dx.doi.org/10.3390/molecules25235508 |
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