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Dual Function of iPSC-Derived Pericyte-Like Cells in Vascularization and Fibrosis-Related Cardiac Tissue Remodeling In Vitro

Myocardial interstitial fibrosis (MIF) is characterized by excessive extracellular matrix (ECM) deposition, increased myocardial stiffness, functional weakening, and compensatory cardiomyocyte (CM) hypertrophy. Fibroblasts (Fbs) are considered the principal source of ECM, but the contribution of per...

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Detalles Bibliográficos
Autores principales: Szepes, Monika, Melchert, Anna, Dahlmann, Julia, Hegermann, Jan, Werlein, Christopher, Jonigk, Danny, Haverich, Axel, Martin, Ulrich, Olmer, Ruth, Gruh, Ina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728071/
https://www.ncbi.nlm.nih.gov/pubmed/33255686
http://dx.doi.org/10.3390/ijms21238947