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Deconvolution of heterogeneous tumor samples using partial reference signals

Deconvolution of heterogeneous bulk tumor samples into distinct cellular populations is an important yet challenging problem, particularly when only partial references are available. A common approach to dealing with this problem is to deconvolve the mixed signals using available references and leve...

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Detalles Bibliográficos
Autores principales: Qin, Yufang, Zhang, Weiwei, Sun, Xiaoqiang, Nan, Siwei, Wei, Nana, Wu, Hua-Jun, Zheng, Xiaoqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728196/
https://www.ncbi.nlm.nih.gov/pubmed/33253170
http://dx.doi.org/10.1371/journal.pcbi.1008452