A novel mouse model of obstructive sleep apnea by bulking agent-induced tongue enlargement results in left ventricular contractile dysfunction

AIMS: Obstructive sleep apnea (OSA) is a widespread disease with high global socio-economic impact. However, detailed pathomechanisms are still unclear, partly because current animal models of OSA do not simulate spontaneous airway obstruction. We tested whether polytetrafluoroethylene (PTFE) inject...

Descripción completa

Detalles Bibliográficos
Autores principales: Lebek, Simon, Hegner, Philipp, Schach, Christian, Reuthner, Kathrin, Tafelmeier, Maria, Maier, Lars Siegfried, Arzt, Michael, Wagner, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728202/
https://www.ncbi.nlm.nih.gov/pubmed/33301470
http://dx.doi.org/10.1371/journal.pone.0243844

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728202/
https://www.ncbi.nlm.nih.gov/pubmed/33301470
http://dx.doi.org/10.1371/journal.pone.0243844

Ejemplares similares