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Systematic clustering algorithm for chromatin accessibility data and its application to hematopoietic cells

The huge amount of data acquired by high-throughput sequencing requires data reduction for effective analysis. Here we give a clustering algorithm for genome-wide open chromatin data using a new data reduction method. This method regards the genome as a string of 1s and 0s based on a set of peaks an...

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Detalles Bibliográficos
Autores principales: Tanaka, Azusa, Ishitsuka, Yasuhiro, Ohta, Hiroki, Fujimoto, Akihiro, Yasunaga, Jun-ichirou, Matsuoka, Masao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728210/
https://www.ncbi.nlm.nih.gov/pubmed/33253153
http://dx.doi.org/10.1371/journal.pcbi.1008422