Inference of mutability landscapes of tumors from single cell sequencing data

One of the hallmarks of cancer is the extremely high mutability and genetic instability of tumor cells. Inherent heterogeneity of intra-tumor populations manifests itself in high variability of clone instability rates. Analogously to fitness landscapes, the instability rates of clonal populations fo...

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Detalles Bibliográficos
Autores principales: Tsyvina, Viachaslau, Zelikovsky, Alex, Snir, Sagi, Skums, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728263/
https://www.ncbi.nlm.nih.gov/pubmed/33253159
http://dx.doi.org/10.1371/journal.pcbi.1008454

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728263/
https://www.ncbi.nlm.nih.gov/pubmed/33253159
http://dx.doi.org/10.1371/journal.pcbi.1008454

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