Generation and validation of versatile inducible CRISPRi embryonic stem cell and mouse model

Clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) 9 has been widely used far beyond genome editing. Fusions of deactivated Cas9 (dCas9) to transcription effectors enable interrogation of the epigenome and controlling of gene expression. However, the large tran...

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Detalles Bibliográficos
Autores principales: Li, Rui, Xia, Xianyou, Wang, Xing, Sun, Xiaoyu, Dai, Zhongye, Huo, Dawei, Zheng, Huimin, Xiong, Haiqing, He, Aibin, Wu, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728392/
https://www.ncbi.nlm.nih.gov/pubmed/33253175
http://dx.doi.org/10.1371/journal.pbio.3000749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728392/
https://www.ncbi.nlm.nih.gov/pubmed/33253175
http://dx.doi.org/10.1371/journal.pbio.3000749

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