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Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts

Chondrocytes proliferate and mature into hypertrophic chondrocytes. Vascular invasion into the cartilage occurs in the terminal hypertrophic chondrocyte layer, and terminal hypertrophic chondrocytes die by apoptosis or transdifferentiate into osteoblasts. Runx2 is essential for osteoblast differenti...

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Detalles Bibliográficos
Autores principales: Qin, Xin, Jiang, Qing, Nagano, Kenichi, Moriishi, Takeshi, Miyazaki, Toshihiro, Komori, Hisato, Ito, Kosei, von der Mark, Klaus, Sakane, Chiharu, Kaneko, Hitomi, Komori, Toshihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728394/
https://www.ncbi.nlm.nih.gov/pubmed/33253203
http://dx.doi.org/10.1371/journal.pgen.1009169