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A novel interaction between soluble epoxide hydrolase and the AT1 receptor in retinal microvascular damage

Clinical studies have suggested that the renin-angiotensin system (RAS) may be a promising therapeutic target in treating diabetic retinopathy (DR). While AT1 receptor blockade decreased the incidence of DR in the DIRECT trial, it did not reduce the DR progression. Lack of understanding of the molec...

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Detalles Bibliográficos
Autores principales: Wang, Mong-Heng, Ibrahim, Ahmed S., Hsiao, George, Tawfik, Amany, Al-Shabrawey, Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728430/
https://www.ncbi.nlm.nih.gov/pubmed/32360774
http://dx.doi.org/10.1016/j.prostaglandins.2020.106449