Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes

We determined differential gene expression in response to high glucose in lymphoblastoid cell lines derived from matched individuals with type 1 diabetes with and without retinopathy. Those genes exhibiting the largest difference in glucose response were assessed for association with diabetic retino...

Descripción completa

Detalles Bibliográficos
Autores principales: Skol, Andrew D, Jung, Segun C, Sokovic, Ana Marija, Chen, Siquan, Fazal, Sarah, Sosina, Olukayode, Borkar, Poulami P, Lin, Amy, Sverdlov, Maria, Cao, Dingcai, Swaroop, Anand, Bebu, Ionut, Stranger, Barbara E, Grassi, Michael A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728435/
https://www.ncbi.nlm.nih.gov/pubmed/33164750
http://dx.doi.org/10.7554/eLife.59980

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728435/
https://www.ncbi.nlm.nih.gov/pubmed/33164750
http://dx.doi.org/10.7554/eLife.59980

Ejemplares similares