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Persulfidation of transcription factor FOXO1 at cysteine 457: A novel mechanism by which H(2)S inhibits vascular smooth muscle cell proliferation
INTRODUCTION: The proliferation of vascular smooth muscle cells (VSMCs) is an important physiological and pathological basis for many cardiovascular diseases. Endogenous hydrogen sulfide (H(2)S), the third gasotransmitter, is found to preserve vascular structure by inhibiting VSMC proliferation. How...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728583/ https://www.ncbi.nlm.nih.gov/pubmed/33318874 http://dx.doi.org/10.1016/j.jare.2020.06.023 |