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Persulfidation of transcription factor FOXO1 at cysteine 457: A novel mechanism by which H(2)S inhibits vascular smooth muscle cell proliferation

INTRODUCTION: The proliferation of vascular smooth muscle cells (VSMCs) is an important physiological and pathological basis for many cardiovascular diseases. Endogenous hydrogen sulfide (H(2)S), the third gasotransmitter, is found to preserve vascular structure by inhibiting VSMC proliferation. How...

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Detalles Bibliográficos
Autores principales: Tian, Xiaoyu, Zhou, Dan, Zhang, Yong, Song, Yunjia, Zhang, Qingyou, Bu, Dingfang, Sun, Yan, Wu, Liling, Long, Yuan, Tang, Chaoshu, Du, Junbao, Huang, Yaqian, Jin, Hongfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728583/
https://www.ncbi.nlm.nih.gov/pubmed/33318874
http://dx.doi.org/10.1016/j.jare.2020.06.023