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Structure-activity relationships study of isothiocyanates for H(2)S releasing properties: 3-Pyridyl-isothiocyanate as a new promising cardioprotective agent
INTRODUCTION: The gasotransmitter hydrogen sulphide (H(2)S), an endogenous ubiquitous signalling molecule, is known for its beneficial effects on different mammalian systems. H(2)S exhibits cardioprotective activity against ischemia/reperfusion (I/R) or hypoxic injury. METHODS: A library of forty-fi...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728584/ https://www.ncbi.nlm.nih.gov/pubmed/33318865 http://dx.doi.org/10.1016/j.jare.2020.02.017 |