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Hippocampal ornithine decarboxylase/spermidine pathway mediates H(2)S-alleviated cognitive impairment in diabetic rats: Involving enhancment of hippocampal autophagic flux

INTRODUCTION: We have previously demonstrated the antagonistic role of hydrogen sulfide (H2S) in the cognitive dysfunction of streptozotocin (STZ)-induced diabetic rats. It has been confirmed that the impaired hippocampal autophagic flux has a key role in the pathogenesis of cognitive impairment and...

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Detalles Bibliográficos
Autores principales: Kang, Xuan, Li, Cheng, Xie, Yan, He, Ling-Li, Xiao, Fan, Zhan, Ke-Bin, Tang, Yi-Yun, Li, Xiang, Tang, Xiao-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728590/
https://www.ncbi.nlm.nih.gov/pubmed/33318864
http://dx.doi.org/10.1016/j.jare.2020.06.007