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SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia

Epigenetic regulations play crucial roles in leukemogenesis and leukemia progression. SUV39H1 is the dominant H3K9 methyltransferase in the hematopoietic system, and its expression declines with aging. However, the role of SUV39H1 via its-mediated repressive modification H3K9me3 in leukemogenesis/le...

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Detalles Bibliográficos
Autores principales: Chu, Yajing, Chen, Yangpeng, Guo, Huidong, Li, Mengke, Wang, Bichen, Shi, Deyang, Cheng, Xuelian, Guan, Jinxia, Wang, Xiaomin, Xue, Chenghai, Cheng, Tao, Shi, Jun, Yuan, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728597/
https://www.ncbi.nlm.nih.gov/pubmed/33037410
http://dx.doi.org/10.1038/s41388-020-01495-6