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SUV39H1 regulates the progression of MLL-AF9-induced acute myeloid leukemia
Epigenetic regulations play crucial roles in leukemogenesis and leukemia progression. SUV39H1 is the dominant H3K9 methyltransferase in the hematopoietic system, and its expression declines with aging. However, the role of SUV39H1 via its-mediated repressive modification H3K9me3 in leukemogenesis/le...
Autores principales: | Chu, Yajing, Chen, Yangpeng, Guo, Huidong, Li, Mengke, Wang, Bichen, Shi, Deyang, Cheng, Xuelian, Guan, Jinxia, Wang, Xiaomin, Xue, Chenghai, Cheng, Tao, Shi, Jun, Yuan, Weiping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728597/ https://www.ncbi.nlm.nih.gov/pubmed/33037410 http://dx.doi.org/10.1038/s41388-020-01495-6 |
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