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Abdominal FLASH irradiation reduces radiation-induced gastrointestinal toxicity for the treatment of ovarian cancer in mice

Radiation therapy is the most effective cytotoxic therapy for localized tumors. However, normal tissue toxicity limits the radiation dose and the curative potential of radiation therapy when treating larger target volumes. In particular, the highly radiosensitive intestine limits the use of radiatio...

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Detalles Bibliográficos
Autores principales: Levy, Karen, Natarajan, Suchitra, Wang, Jinghui, Chow, Stephanie, Eggold, Joshua T., Loo, Phoebe E., Manjappa, Rakesh, Melemenidis, Stavros, Lartey, Frederick M., Schüler, Emil, Skinner, Lawrie, Rafat, Marjan, Ko, Ryan, Kim, Anna, H. Al-Rawi, Duaa, von Eyben, Rie, Dorigo, Oliver, Casey, Kerriann M., Graves, Edward E., Bush, Karl, Yu, Amy S., Koong, Albert C., Maxim, Peter G., Loo, Billy W., Rankin, Erinn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728763/
https://www.ncbi.nlm.nih.gov/pubmed/33303827
http://dx.doi.org/10.1038/s41598-020-78017-7