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Phosphatidylinositol synthesis, its selective salvage, and inter-regulation of anionic phospholipids in Toxoplasma gondii

Phosphatidylinositol (PtdIns) serves as an integral component of eukaryotic membranes; however, its biosynthesis in apicomplexan parasites remains poorly understood. Here we show that Toxoplasma gondii—a common intracellular pathogen of humans and animals—can import and co-utilize myo-inositol with...

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Detalles Bibliográficos
Autores principales: Ren, Bingjian, Kong, Pengfei, Hedar, Fatima, Brouwers, Jos F., Gupta, Nishith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728818/
https://www.ncbi.nlm.nih.gov/pubmed/33303967
http://dx.doi.org/10.1038/s42003-020-01480-5