Divergent Effects of the N-Methyl-D-Aspartate Receptor Antagonist Kynurenic Acid and the Synthetic Analog SZR-72 on Microcirculatory and Mitochondrial Dysfunction in Experimental Sepsis

Introduction: Sepsis is a dysregulated host response to infection with macro- and microhemodynamic deterioration. Kynurenic acid (KYNA) is a metabolite of the kynurenine pathway of tryptophan catabolism with pleiotropic cell-protective effects under pro-inflammatory conditions. Our aim was to invest...

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Detalles Bibliográficos
Autores principales: Juhász, László, Rutai, Attila, Fejes, Roland, Tallósy, Szabolcs P., Poles, Marietta Z., Szabó, Andrea, Szatmári, István, Fülöp, Ferenc, Vécsei, László, Boros, Mihály, Kaszaki, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729001/
https://www.ncbi.nlm.nih.gov/pubmed/33330526
http://dx.doi.org/10.3389/fmed.2020.566582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729001/
https://www.ncbi.nlm.nih.gov/pubmed/33330526
http://dx.doi.org/10.3389/fmed.2020.566582

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