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Divergent Effects of the N-Methyl-D-Aspartate Receptor Antagonist Kynurenic Acid and the Synthetic Analog SZR-72 on Microcirculatory and Mitochondrial Dysfunction in Experimental Sepsis

Introduction: Sepsis is a dysregulated host response to infection with macro- and microhemodynamic deterioration. Kynurenic acid (KYNA) is a metabolite of the kynurenine pathway of tryptophan catabolism with pleiotropic cell-protective effects under pro-inflammatory conditions. Our aim was to invest...

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Detalles Bibliográficos
Autores principales:	Juhász, László, Rutai, Attila, Fejes, Roland, Tallósy, Szabolcs P., Poles, Marietta Z., Szabó, Andrea, Szatmári, István, Fülöp, Ferenc, Vécsei, László, Boros, Mihály, Kaszaki, József
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729001/ https://www.ncbi.nlm.nih.gov/pubmed/33330526 http://dx.doi.org/10.3389/fmed.2020.566582

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