Viral macrodomains: a structural and evolutionary assessment of the pharmacological potential

Viral macrodomains possess the ability to counteract host ADP-ribosylation, a post-translational modification implicated in the creation of an antiviral environment via immune response regulation. This brought them into focus as promising therapeutic targets, albeit the close homology to some of the...

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Detalles Bibliográficos
Autores principales: Rack, Johannes Gregor Matthias, Zorzini, Valentina, Zhu, Zihan, Schuller, Marion, Ahel, Dragana, Ahel, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729036/
https://www.ncbi.nlm.nih.gov/pubmed/33202171
http://dx.doi.org/10.1098/rsob.200237

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729036/
https://www.ncbi.nlm.nih.gov/pubmed/33202171
http://dx.doi.org/10.1098/rsob.200237

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