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Reversible N6-methyladenosine of RNA: The regulatory mechanisms on gene expression and implications in physiology and pathology

N6-methyladenosine (m6A) is the most abundant inner RNA modification in eukaryotes. Due to the development of RNA sequencing technology, the distribution pattern of m6A in the transcriptome has been uncovered. Dynamically, the reversible N6-methylation is mediated by two types of proteins, which are...

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Detalles Bibliográficos
Autores principales: Fang, Xinyu, Li, Mengyang, Yu, Tao, Liu, Gaoli, Wang, Jianxun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729110/
https://www.ncbi.nlm.nih.gov/pubmed/33335958
http://dx.doi.org/10.1016/j.gendis.2020.06.011