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PPARγ S273 Phosphorylation Modifies the Dynamics of Coregulator Proteins Recruitment

The nuclear receptor PPARγ is essential to maintain whole-body glucose homeostasis and insulin sensitivity, acting as a master regulator of adipogenesis, lipid, and glucose metabolism. Its activation through natural or synthetic ligands induces the recruitment of coactivators, leading to transcripti...

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Detalles Bibliográficos
Autores principales: Dias, Marieli Mariano Gonçalves, Batista, Fernanda Aparecida Heleno, Tittanegro, Thais Helena, de Oliveira, André Gustavo, Le Maire, Albane, Torres, Felipe Rafael, Filho, Helder Veras Ribeiro, Silveira, Leonardo Reis, Figueira, Ana Carolina Migliorini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729135/
https://www.ncbi.nlm.nih.gov/pubmed/33329381
http://dx.doi.org/10.3389/fendo.2020.561256