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PPARγ S273 Phosphorylation Modifies the Dynamics of Coregulator Proteins Recruitment
The nuclear receptor PPARγ is essential to maintain whole-body glucose homeostasis and insulin sensitivity, acting as a master regulator of adipogenesis, lipid, and glucose metabolism. Its activation through natural or synthetic ligands induces the recruitment of coactivators, leading to transcripti...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729135/ https://www.ncbi.nlm.nih.gov/pubmed/33329381 http://dx.doi.org/10.3389/fendo.2020.561256 |