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PPARγ S273 Phosphorylation Modifies the Dynamics of Coregulator Proteins Recruitment
The nuclear receptor PPARγ is essential to maintain whole-body glucose homeostasis and insulin sensitivity, acting as a master regulator of adipogenesis, lipid, and glucose metabolism. Its activation through natural or synthetic ligands induces the recruitment of coactivators, leading to transcripti...
Autores principales: | Dias, Marieli Mariano Gonçalves, Batista, Fernanda Aparecida Heleno, Tittanegro, Thais Helena, de Oliveira, André Gustavo, Le Maire, Albane, Torres, Felipe Rafael, Filho, Helder Veras Ribeiro, Silveira, Leonardo Reis, Figueira, Ana Carolina Migliorini |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7729135/ https://www.ncbi.nlm.nih.gov/pubmed/33329381 http://dx.doi.org/10.3389/fendo.2020.561256 |
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